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Pezzullo serves as a founding Co-Director of the , which engages in inclusive partnerships, projects, and policy research to advance climate justice in the transition from a carbon-based extractive economy to a sustainable, living culture. She also is a co-director of , which fosters creative climate communication for decision-makers, youth, and frontline communities.

Pezzullo authored the highly-regarded book, (University of Alabama Press, 2007), which won four book awards. She also has coauthored and/or (co)edited five additional books, including the textbook (Sage,  2018), which has a new edition forthcoming in 2021. She has a forthcoming coedited book in English and Chinese,  (Michigan State University Press and Communication University of China, 2020). Pezzullo also has colaunched a new University of California book series: .

She has been an invited lecturer throughout the US and internationally, including the Grand Amphithéâtre de la Sorbonne, Université de Paris-Sorbonne in Paris, France, Fudan University in Shanghai, China.