biomedical

Two from ECEE earn AB Nexus grants for collaborations with CU Anschutz

Anonymous — Wed, 16 Nov 2022 16:52:54 +0000

Two from ECEE earn AB Nexus grants for collaborations with CU Anschutz Anonymous (not verified) Wed, 11/16/2022 - 09:52

Juliet Gopinath will tackle novel neurophotonics methods to access deep brain structures for decision making, while Zoya Popovic will advance technique for noninvasive brain temperature monitoring during cardiac surgery.

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Researchers make strides in commercializing simplified dual-comb spectroscopy

Anonymous — Tue, 30 Aug 2022 13:57:25 +0000

Researchers make strides in commercializing simplified dual-comb spectroscopy Anonymous (not verified) Tue, 08/30/2022 - 07:57

Emily Adams

Huang (left) and a graduate student discuss a project in their lab.

It is sometimes said that science is about truth, while engineering is about compromise.

With one laser project in his lab in the Department of Electrical, Computer and Energy Engineering, Shu-Wei Huang and his team are working on a compromise in order to find new applications for a powerful new technology and make it easier to commercialize.

As they looked at the innovative and extremely precise dual-comb spectroscopy being honed by mechanical engineering Associate Professor Greg Rieker and others, Huang’s team saw an opportunity to expand its applications.

“We've been trying to see whether we can compromise the performance a little bit to greatly simplify the architecture,” Huang said. “The application that we are especially interested in is the biomedical application because in biomedical applications, you don't need the same resolution you need to do something like methane detection.”

The result is the counter-propagating all-normal dispersion (CANDi) fiber laser, which won Bowen Li, a postdoctoral researcher in Huang’s lab, a prestigious award from Optica in 2021.

The key has been a redesigned laser cavity that allows for light to travel both clockwise and counterclockwise, which essentially makes two lasers out of one laser cavity. That, in turn, decreases the number of complex electronics needed to configure two lasers in dual-comb devices, Huang explained.

“We reduce the complexity in the laser design, and we have to compromise the precision a little bit, but it's still much better than the state of art tools used in biomedical applications,” Huang said.

In the team’s most recent Optica paper, they introduced new techniques to reduce the CANDi laser’s relative timing jitter, further proving that the laser will be a good option for a host of applications. That work won PhD student Neeraj Prakash a best poster award at Optica’s 2021 Laser Congress.

Huang said they’ve been working with a startup company in Taiwan that is interested in using CANDi for terahertz imaging – often used in screening for security and drugs. A lab at Colorado State University is also experimenting with the laser for Raman spectroscopy, which has applications in pharmaceuticals and water-quality monitoring.

“CANDi is a new fiber laser architecture and right now, we are working on several projects to unveil its full potential for dual-comb applications,” Huang said.

Read the Optica paper

Shu-Wei Huang and his team are working on a compromise in order to find new applications for a powerful new technology.

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Research collaboration explores multiple methods for brain imaging

Anonymous — Wed, 13 Apr 2022 20:31:33 +0000

Research collaboration explores multiple methods for brain imaging Anonymous (not verified) Wed, 04/13/2022 - 14:31

Researchers at the University of Colorado Boulder and Anschutz Medical Campus are exploring several imaging techniques aimed at creating lightweight miniature microscopes.

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Detailed time-lapse images of brain cells could lead to new insights for neurological disorders

Anonymous — Wed, 30 Mar 2022 13:52:56 +0000

Detailed time-lapse images of brain cells could lead to new insights for neurological disorders Anonymous (not verified) Wed, 03/30/2022 - 07:52

In the journal Biomedical Optics Express, CU researchers describe their new SIMscope3D, a miniature microscope designed for high-resolution 3D images.

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