By Lyanna Kessler
In the winter of 2022, I applied to be a student in a course on听
neuroinflammation, a course that takes place in Venice, Italy. It seemed like听
a great opportunity, where I could learn about the topics that interest me听
most in the beautiful Venetian atmosphere. I remember as an undergraduate
I first heard there was a link between the brain and the immune system in听
cases of Alzheimer鈥檚 disease. It sparked so many questions for me, which led
me to focus my PhD research on neuroimmunology (and its subtopics, such听
as neuroinflammation). Specifically, I want to research the mechanisms of听
how a particular bacteria, Mycobacterium vaccae, can reduce听
neuroinflammation. Being new to the field, I felt compelled to attend this听
course to learn from the leading international experts. Thankfully I was听
accepted into the course and in May 2022, I was off to the Neuroscience听
School of Advanced Studies in Italy.
Much like the Venetian canals, it turns out the field of neuroimmunology is听
filled with twists and turns. Where one speaker believed blood-brain barrier听
permeability was possible, another did not. Where a reduction of anhedonia听
was expected, there was not. Different studies on similar models would point
in different directions. It was thrilling to hear about research so fresh, even if听
we don鈥檛 have all the answers yet. When we do have answers, to me it feels听
like we鈥檝e discovered hidden continents. I was excited to learn that听
microglia, the immune cells of the brain, form connected networks when听
laden with toxins. Our conference host, Robert Dantzer, compared the field听
of neuroinflammation to a statue series by Bruno Catalano, 鈥淧ierre David听
Triptyque鈥� (pictured here), saying that we were finally starting to see an听
outline of the big picture, but key gaps remain. I had the opportunity to听
present my research topic to many different speakers and get feedback,听
which has significantly strengthened my project. Of course, I got to explore听
the city as well, with my crumpled map and vaporetto schedule in hand. I ate
amazing Italian cuisine, visited museums, and walked or boated everywhere.
By the end of my week-long stay, I felt like the map of Venice was part of听
me, with canals like veins and alleys like nerves. It was everything I had听
hoped, both an academically and personally enriching experience.
